High speed, wide velocity dynamic range Doppler optical coherence tomography (Part III): in vivo endoscopic imaging of blood flow in the rat and human gastrointestinal tracts.

نویسندگان

  • Victor X D Yang
  • Maggie Gordon
  • Shou-Jiang Tang
  • Norman Marcon
  • Geoffrey Gardiner
  • Bing Qi
  • Stuart Bisland
  • Emily Seng-Yue
  • Stewart Lo
  • Julius Pekar
  • Brian Wilson
  • I Vitkin
چکیده

We previously described a fiber based Doppler optical coherence tomography system [1] capable of imaging embryo cardiac blood flow at 4~16 frames per second with wide velocity dynamic range [2]. Coupling this system to a linear scanning fiber optical catheter design that minimizes friction and vibrations, we report here the initial results of in vivo endoscopic Doppler optical coherence tomography (EDOCT) imaging in normal rat and human esophagus. Microvascular flow in blood vessels less than 100 microm diameter was detected using a combination of color-Doppler and velocity variance imaging modes, during clinical endoscopy using a mobile EDOCT system.

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عنوان ژورنال:
  • Optics express

دوره 11 19  شماره 

صفحات  -

تاریخ انتشار 2003